Journal: Cells

Article Title: Mesenchymal Stem Cell-Derived Exosomes: Applications in Regenerative Medicine

doi: 10.3390/cells10081959

Figure Lengend Snippet: MSC-derived exosomes in wound healing therapies.

Article Snippet: (Cooper et al., 2018) [ ] , Human ADMSCs , ExoQuick-TC kit , 90–100 nm , NTA , Six-month-old male Fischer 344 rats , Injection of conditioned media from ZenBio™ ADSC (20 μL) or control (unconditioned) media (20 μL) , Increased wound healing through increased migration and proliferation of keratinocytes and fibroblasts.

Techniques: Isolation, Centrifugation, Activity Assay, Injection, Migration, Transplantation Assay

Journal: PLoS ONE

Article Title: Chondroitin Sulfate- and Decorin-Based Self-Assembling Scaffolds for Cartilage Tissue Engineering

doi: 10.1371/journal.pone.0157603

Figure Lengend Snippet: (A) Toluidine blue staining (sulfated GAGs) of 3D ADSC constructs cultured in chondrogenic medium. (B) Toluidine blue staining of 3D AC constructs cultured in expansion, control and chondrogenic media. (C) Von Kossa staining (indicating calcium mineralization) of 3D ADSC constructs cultured in chondrogenic medium. (D) Von Kossa staining of 3D AC constructs cultured in chondrogenic medium.

Article Snippet: ADSCs (PT-5006, Lonza) (<6th passage) were cultured in 175 cm 2 flasks in ADSC Basal Medium (ADSC-BM) (PT-3273, Lonza) supplemented with ADSC Growth Medium (ADSC-GM) SingleQuots (PT-4503, Lonza).

Techniques: Staining, Construct, Cell Culture, Control

Journal: International Journal of Molecular Sciences

Article Title: Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn’s Disease: Rationale, Clinical Results and Perspectives

doi: 10.3390/ijms22189967

Figure Lengend Snippet: Schematic representation of anoperineal fistulas in Crohn’s disease and of adipose-derived stem cell injections. The different types of fistulas are drawn in red. According to Park’s classification: 1: superficial; 2: inter-sphincteric; 3: trans-sphincter; 4: supra-sphincteric; 5: extra-sphincteric. According to the American Gastroenterological Association: simple fistulas = 1 + 2; complex fistulas = 3 + 4 + 5. In blue, different ADSC routes that are generally applied in refractory complex fistulas: 1: via the internal orifice of the fistula; 2: via the external orifice of the fistula; 3: in the peri-fistula space.

Article Snippet: NCT03466515 Stem Cell Treatment of Complex Crohn’s Perianal Fistula. A Pilot Study Denmark , I (20) , Injection in and around the fistula track of autologous fat tissue and ADSC from SVF (Cytori Celusion system ® ) , Healing (clinical + MRI), time to healing, AE.

Techniques: Derivative Assay

Journal: International Journal of Molecular Sciences

Article Title: Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn’s Disease: Rationale, Clinical Results and Perspectives

doi: 10.3390/ijms22189967

Figure Lengend Snippet: Main ongoing trials applying adipose-derived stem cells for Crohn’s disease anoperineal fistula.

Article Snippet: NCT03466515 Stem Cell Treatment of Complex Crohn’s Perianal Fistula. A Pilot Study Denmark , I (20) , Injection in and around the fistula track of autologous fat tissue and ADSC from SVF (Cytori Celusion system ® ) , Healing (clinical + MRI), time to healing, AE.

Techniques: Injection, Derivative Assay

Journal: International Journal of Molecular Sciences

Article Title: Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn’s Disease: Rationale, Clinical Results and Perspectives

doi: 10.3390/ijms22189967

Figure Lengend Snippet: Schematic representation of anoperineal fistulas in Crohn’s disease and of adipose-derived stem cell injections. The different types of fistulas are drawn in red. According to Park’s classification: 1: superficial; 2: inter-sphincteric; 3: trans-sphincter; 4: supra-sphincteric; 5: extra-sphincteric. According to the American Gastroenterological Association: simple fistulas = 1 + 2; complex fistulas = 3 + 4 + 5. In blue, different ADSC routes that are generally applied in refractory complex fistulas: 1: via the internal orifice of the fistula; 2: via the external orifice of the fistula; 3: in the peri-fistula space.

Article Snippet: NCT03913572 Treatment of Perianal Disease Using Adipose-derived Stem Cells USA , Retrospective, observational (25) , Group 1: surgery + one single injection of ADSC derived from SVF (Revolve System—Acelity ® ) Group 2: surgery alone , Healing at 4 months Clinical + MRI Assessment of PDAI + Adverse Events.

Techniques: Derivative Assay

Journal: International Journal of Molecular Sciences

Article Title: Adipose-Derived Stem Cells in the Treatment of Perianal Fistulas in Crohn’s Disease: Rationale, Clinical Results and Perspectives

doi: 10.3390/ijms22189967

Figure Lengend Snippet: Main ongoing trials applying adipose-derived stem cells for Crohn’s disease anoperineal fistula.

Article Snippet: NCT03913572 Treatment of Perianal Disease Using Adipose-derived Stem Cells USA , Retrospective, observational (25) , Group 1: surgery + one single injection of ADSC derived from SVF (Revolve System—Acelity ® ) Group 2: surgery alone , Healing at 4 months Clinical + MRI Assessment of PDAI + Adverse Events.

Techniques: Injection, Derivative Assay

Journal: International Journal of Telerehabilitation

Article Title: Influence of Smartphones and Software on Acoustic Voice Measures

doi: 10.5195/ijt.2016.6202

Figure Lengend Snippet: Acoustic Measures, Definition, Task, and Software

Article Snippet: If the SLP does not have access to KayPENTAX’s software (i.e., MDVP and ADSV), the recommended minimum acoustic instrumented measures by SIG 3 of ASHA can still be completed using Praat, a free software program downloaded from the internet.

Techniques: Software

Journal: International Journal of Telerehabilitation

Article Title: Influence of Smartphones and Software on Acoustic Voice Measures

doi: 10.5195/ijt.2016.6202

Figure Lengend Snippet: Means and Standard Deviations (in Parentheses) of the Dependent Variables for Women across Utterance (i.e., /a/ and “we were away a year ago”), Software (i.e., Multi-dimensional Voice Program (MDVP), Analysis of Dysphonia in Speech and Voice (ADSV), and Praat), and Recording Device (i.e., iPhone5 (iPh5), iPhone6s (iPh6s), Samsung Galaxy5 (SG5), and Head-mounted Microphone (HeadMic)

Article Snippet: If the SLP does not have access to KayPENTAX’s software (i.e., MDVP and ADSV), the recommended minimum acoustic instrumented measures by SIG 3 of ASHA can still be completed using Praat, a free software program downloaded from the internet.

Techniques: Software

Journal: International Journal of Telerehabilitation

Article Title: Influence of Smartphones and Software on Acoustic Voice Measures

doi: 10.5195/ijt.2016.6202

Figure Lengend Snippet: Means and Standard Deviations (in Parentheses) of the Dependent Variables for Men across Utterance (i.e., /a/ and “we were away a year ago”), Software (i.e., Multi-dimensional Voice Program (MDVP), Analysis of Dysphonia in Speech and Voice (ADSV), and Praat), and Recording Device (i.e., iPhone5 (iPh5), iPhone6s (iPh6s), Samsung Galaxy5 (SG5), and Head-mounted Microphone (HeadMic)

Article Snippet: If the SLP does not have access to KayPENTAX’s software (i.e., MDVP and ADSV), the recommended minimum acoustic instrumented measures by SIG 3 of ASHA can still be completed using Praat, a free software program downloaded from the internet.

Techniques: Software

Journal: International Journal of Molecular Sciences

Article Title: ADSC-Based Cell Therapies for Musculoskeletal Disorders: A Review of Recent Clinical Trials

doi: 10.3390/ijms221910586

Figure Lengend Snippet: Summary of clinical studies examined therapeutic use of hADSCs on arthritis for the last 10 years.

Article Snippet: 10 , Subtalar joint arthritis , 52 (56.9: 20.3–79.6) 6 , Allogeneic , ADSC loaded, partially demineralized cancellous bone (AlloSource) was grafted , Good clinical outcomes in spite of the high non-union rates , 2019 , [ ] .

Techniques: Derivative Assay, Injection, Activity Assay, Isolation, Functional Assay

Journal: International Journal of Molecular Sciences

Article Title: ADSC-Based Cell Therapies for Musculoskeletal Disorders: A Review of Recent Clinical Trials

doi: 10.3390/ijms221910586

Figure Lengend Snippet: Summary of clinical studies involving the use of isolated hADSCs on arm disorders for the last 10 years.

Article Snippet: 10 , Subtalar joint arthritis , 52 (56.9: 20.3–79.6) 6 , Allogeneic , ADSC loaded, partially demineralized cancellous bone (AlloSource) was grafted , Good clinical outcomes in spite of the high non-union rates , 2019 , [ ] .

Techniques: Isolation, Injection, Derivative Assay, Control